Minoxidil was widely known as Loniten and was taken orally to control high blood
pressure, nevertheless an interesting side effect was founded which was: hair growth.Minoxidil
may cause increased growth or darkening of fine body hairs, or in some cases, significant
hair growth. When the medication is discontinued, the hair loss will return to normal
rate within 30 to 60 days. Upjhn Corporation produced the 1st topical solution that
contained 2% minoxidil to be used to treat baldness.
The mechanism by which minoxidil promotes hair growth is not fully understood. Minoxidil
contains the nitric oxide chemicals moiety could possibly act as a nitric oxide
agonist. Like wise minoxidil is a potassium channel opener, causing hyperpolarisations
of cell membranes. Minoxidill is less effective when combating large areas of hair
loss. The effectiveness ofminoxidil is established in younger men and for those
who are suffering from hair loss less then 5 years.
Side effects of Minoxidil
Common side effects of minoxidil include burning or irritation of the eye, itching,
redness or irritation at the treated area, as well as unwanted hair growth elsewhere
on the body. Users should stop treatment and seek medical attention right away if
they experience any of the following serious side effects: Severe allergic reactions
(rash; hives; itching; difficulty breathing; tightness in the chest; swelling of
the mouth, face, lips, or tongue); chest pain; dizziness; fainting; fast heartbeat;
sudden, unexplained weight gain; swollen hands or feet.
Alcohol and propylene glycol present in some topical preparations may dry the scalp,
resulting in dandruff and contact dermatitis.